My interests in the Digital Humanities reflect my own understanding of this growing field, primarily in that I focus on databases, spatial analysis, modeling and representation of processes using abstraction and animation. To that end, I've found myself using a variety of toolsets to create interesting visualizations or analysis, which include GIMP, Inkscape, ArcGIS, MySQL, ActionScript, PHP, et cetera.
My biggest concern with the current state of production of humanities digital media is the scant attention to peer review in the evaluation of such media. Combined with questions of long-term data integrity, I think this is the biggest hurdle for the Digital Humanities to overcome.